Hong Jiang Selected Research

Amyloid Plaque

1/2022	APOE Antibody Inhibits Aβ-Associated Tau Seeding and Spreading in a Mouse Model.
1/2021	APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function.
4/2020	Altered clearance of beta-amyloid from the cerebrospinal fluid following subchronic lead exposure in rats: Roles of RAGE and LRP1 in the choroid plexus.
1/2019	TREM2 function impedes tau seeding in neuritic plaques.
1/2018	ApoE facilitates the microglial response to amyloid plaque pathology.
1/2018	Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation.
11/2017	Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
11/2016	The Effects of Peripheral and Central High Insulin on Brain Insulin Signaling and Amyloid-β in Young and Old APP/PS1 Mice.
11/2015	Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models.
5/2014	Anti-ApoE antibody given after plaque onset decreases Aβ accumulation and improves brain function in a mouse model of Aβ amyloidosis.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hong Jiang Research Topics

Disease

214	Neoplasms (Cancer) 05/2024 - 02/2003
92	Parkinson Disease (Parkinson's Disease) 05/2024 - 01/2003
88	Inflammation (Inflammations) 04/2024 - 05/2002
67	Alzheimer Disease (Alzheimer's Disease) 02/2024 - 05/2004
52	Ischemia 02/2024 - 07/2005
51	Myocardial Ischemia (Ischemic Heart Diseases) 09/2023 - 03/2005
49	Myocardial Infarction 03/2024 - 03/2005
45	Fibrosis (Cirrhosis) 05/2024 - 03/2006
42	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2023 - 01/2008
39	Reperfusion Injury 09/2023 - 06/2004
38	Infections 12/2023 - 01/2002
35	Hypoxia (Hypoxemia) 02/2024 - 10/2008
35	Glioma (Gliomas) 02/2024 - 01/2003
35	Infarction (Infarctions) 12/2023 - 12/2004
34	Cardiovascular Diseases (Cardiovascular Disease) 02/2024 - 12/2010
34	Atrial Fibrillation 01/2023 - 07/2005
33	Cognitive Dysfunction 03/2024 - 10/2011
30	Atherosclerosis 05/2024 - 03/2005
30	Heart Failure 02/2024 - 03/2005
23	Cardiac Arrhythmias (Arrythmia) 01/2024 - 03/2005
22	Lung Neoplasms (Lung Cancer) 02/2023 - 04/2011
22	Neoplasm Metastasis (Metastasis) 12/2022 - 10/2009
20	Disease Progression 01/2024 - 04/2013
19	Wounds and Injuries (Trauma) 12/2023 - 09/2014
19	Neuroinflammatory Diseases 08/2023 - 05/2013
19	Cardiomegaly (Heart Hypertrophy) 01/2022 - 02/2010
18	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 11/2023 - 06/2005
18	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2023 - 02/2012
17	Hypertension (High Blood Pressure) 06/2024 - 09/2006
17	Coronary Artery Disease (Coronary Atherosclerosis) 12/2022 - 08/2002
16	Stroke (Strokes) 02/2024 - 08/2005
15	Pain (Aches) 01/2023 - 09/2013
15	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2023 - 10/2006
15	Amyloid Plaque 01/2022 - 12/2005
15	Thrombosis (Thrombus) 11/2021 - 02/2004
14	Mitochondrial Diseases (Mitochondrial Disease) 03/2024 - 04/2008
14	Ganglion Cysts (Ganglion) 12/2022 - 06/2012
14	Hyperplasia 01/2022 - 05/2009
14	Vascular System Injuries 12/2020 - 11/2002
13	Intervertebral Disc Displacement (Herniated Disc) 03/2024 - 03/2009
13	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 12/2023 - 03/2003
13	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 12/2023 - 01/2011
13	Colorectal Neoplasms (Colorectal Cancer) 03/2023 - 09/2011
12	Carcinoma (Carcinomatosis) 04/2024 - 01/2009
12	Body Weight (Weight, Body) 04/2022 - 02/2010
12	Necrosis 01/2022 - 09/2006
11	Multiple Sclerosis 12/2023 - 01/2016
11	Type 2 Diabetes Mellitus (MODY) 10/2023 - 09/2012
11	Melanoma (Melanoma, Malignant) 10/2023 - 01/2015

Drug/Important Bio-Agent (IBA)

147	Proteins (Proteins, Gene)FDA Link 05/2024 - 01/2004
76	Biomarkers (Surrogate Marker)IBA 01/2024 - 08/2008
52	IronIBA 11/2023 - 01/2003
41	Retinaldehyde (Retinal)IBA 07/2023 - 06/2012
40	CytokinesIBA 12/2023 - 10/2008
32	Amyloid (Amyloid Fibrils)IBA 02/2024 - 02/2008
32	Messenger RNA (mRNA)IBA 01/2024 - 10/2002
31	Apolipoproteins E (ApoE)IBA 01/2024 - 05/2004
29	HMGB1 Protein (HMG1)IBA 01/2022 - 08/2009
28	LipidsIBA 02/2023 - 05/2002
27	DNA (Deoxyribonucleic Acid)IBA 01/2024 - 01/2002
27	EnzymesIBA 05/2023 - 10/2002
25	AntioxidantsIBA 04/2023 - 07/2009
24	CollagenIBA 01/2024 - 01/2004
23	Therapeutic UsesIBA 01/2023 - 01/2003
22	Peptides (Polypeptides)IBA 12/2023 - 09/2007
21	ApolipoproteinsIBA 01/2024 - 05/2004
21	Interleukin-6 (Interleukin 6)IBA 12/2023 - 10/2008
21	salicylhydroxamic acid (SHAM)IBA 01/2023 - 06/2007
20	MicroRNAs (MicroRNA)IBA 01/2024 - 08/2010
19	RNA (Ribonucleic Acid)IBA 01/2023 - 01/2002
18	Glucose (Dextrose)FDA LinkGeneric 12/2023 - 12/2008
18	Long Noncoding RNAIBA 11/2023 - 01/2017
18	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2022 - 03/2005
17	GhrelinIBA 10/2022 - 11/2005
16	Small Interfering RNA (siRNA)IBA 05/2024 - 08/2008
15	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2023 - 10/2009
14	Sevoflurane (Ultane)FDA LinkGeneric 03/2024 - 04/2015
14	C-Reactive ProteinIBA 11/2023 - 05/2002
14	Transcription Factors (Transcription Factor)IBA 05/2022 - 03/2008
14	polyglutamineIBA 01/2021 - 08/2008
13	SynucleinsIBA 05/2024 - 06/2013
13	Phosphotransferases (Kinase)IBA 12/2023 - 07/2005
13	Indicators and Reagents (Reagents)IBA 11/2023 - 10/2002
13	CurcuminIBA 03/2023 - 01/2011
12	CalciumIBA 04/2024 - 03/2005
12	NF-kappa B (NF-kB)IBA 12/2023 - 03/2005
12	AcidsIBA 05/2023 - 07/2006
12	AntigensIBA 01/2023 - 11/2009
12	Isoflurane FDA LinkGeneric 01/2023 - 12/2008
12	Neuroprotective AgentsIBA 01/2021 - 11/2006
11	Cisplatin (Platino)FDA LinkGeneric 01/2024 - 09/2003

Therapy/Procedure

151	Therapeutics 05/2024 - 03/2003
29	Drug Therapy (Chemotherapy) 01/2024 - 05/2003
19	Vagus Nerve Stimulation 03/2024 - 11/2013
17	Chinese Traditional Medicine (Traditional Chinese Medicine) 03/2024 - 12/2006
17	Transplantation 01/2022 - 06/2006
15	Aftercare (After-Treatment) 11/2023 - 09/2007
14	Immunotherapy 02/2024 - 11/2012
14	Ligation 12/2022 - 06/2008
12	Catheter Ablation 01/2023 - 04/2006